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. 2000 Aug 1;28(15):2866–2872. doi: 10.1093/nar/28.15.2866

Figure 1.

Figure 1

Sequence alignment of CRSs from different species. Schematic alignment of representative CRSs. Eukaryotic CRSs, compared to prokaryotic (Escherichia coli) and archeaic (Aeropyrum pernix) CRSs, have two characteristics, a large insertion of ∼100 residues within a Rossmann fold and an extension at the C-terminus. The reported sequence of human CRS (P49589, H.sapiens 1) lacks the C-terminal extension (12) but was revised to have the C-terminal extension (H.sapiens 2) (16). These two sequences are to be corrected.