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. 2023 Jun 15;23:394. doi: 10.1186/s12903-023-03110-y

Table 4.

Summary of findings: outcome in permanent teeth for 2 or more years of follow-up

Secondary Caries outcome in permanent teeth for 2 or more years of follow-up
Patient or population: Permanent teeth
Interventions: GIC: Glass Ionomer Cement; RMGIC: Resin Modified Glass Ionomer Cement; RC: Resin Composite; AAG:Amalgam; FAAG: Fluoride-containing Amalgam; COMPOMER
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Interventions Anticipated absolute effects
with intervention
Relative effect (95% CI) № of participants (studies) Certainty of the evidence (GRADE) Ranking
GIC 2 per 100 RR 0.50d (0.28 to 0.91) 1571 (14 Clinical Trials)

⨁⨁⨁◯

Moderatea

1º—P-score = 0.83
FAAG 16 per 100 RR 0.95e (0.45 to 2.00) 309 (6 Clinical Trials)

⨁⨁◯◯

Lowa,b

2º—P-score = 0.83
RMGIC 11 per 100 RR 1.33e (0.70 to 2.54) 141 (5 Clinical Trials)

⨁⨁◯◯

Lowa,b

3º—P-score = 0.59
AAG 24 per 100 RR 1.79e (1.04 to 3.09) 390 (7 Clinical Trials)

⨁⨁◯◯

Lowa,b

4º—P-score = 0.32
RC 6 per 100 RR 2.00e (1.10 to 3.64) 728 (13 Clinical Trials)

⨁◯◯◯

Very lowa,c

5º—P-score = 0.25
COMPOMER 3 per 100 RR 3.20e (0.59 to 17.33) 79 (2 Clinical Trials)

⨁◯◯◯

Very lowa,c

1º—P-score = 0.18

aOne-level reduction due to some concerns regarding the risk of bias in the primary studies

bOne-level reduction due to imprecision

cSignificant concerns regarding the imprecision of the estimates

dThe relative effect is based on comparison with RC

eThe relative effect is based on comparison with GIC