Table 2.

SIFT and PolyPhen-2 predicted non-synonymous SNPs

No	ID of nsSNPs	AA positions	SIFT	Score	PolyPhen-2	Score	No	ID of nsSNPs	AA positions	SIFT	Score	PolyPhen-2	Score
1	rs61757480	I291T	DEL	0.001	Prob Dam	1	26	rs370857003	S58F	DEL	0	Prob Dam	1
2	rs61741624	V395I	DEL	0.035	Prob Dam	1	27	rs370665830	Q588H	DEL	0.007	Prob Dam	0.979
3	rs140806973	A336V	DEL	0.035	Prob Dam	1	28	rs143125991	G25V	DEL	0.016	Prob Dam	0.982
4	rs80330149	G298R	DEL	0.004	Prob Dam	1	29	rs146979323	R565W	DEL	0	Prob Dam	1
5	rs137870001	R270H	DEL	0.02	Prob Dam	1	30	rs372028526	R248H	DEL	0.002	Prob Dam	1
6	rs138927279	C567Y	DEL	0	Prob Dam	1	31	rs372067284	T668M	DEL	0.001	Prob Dam	1
7	rs139835107	F81L	DEL	0.019	BENIGN	0.416	32	rs372614431	R817C	DEL	0.001	Prob Dam	0.995
8	rs140595148	Q616H	DEL	0	Prob Dam	1	33	rs372664222	R713L	DEL	0.004	Prob Dam	0.998
9	rs140914273	R572H	DEL	0.017	Prob Dam	1	34	rs374592996	Y148C	DEL	0.001	Prob Dam	0.999
10	rs141374503	R565Q	DEL	0.007	Prob Dam	1	35	rs374628791	R55L	DEL	0.018	BENIGN	0.223
11	rs142268705	A370T	DEL	0.002	Prob Dam	1	36	rs374705972	R435H	DEL	0.029	Prob Dam	1
12	rs142781084	Q927R	DEL	0.017	Prob Dam	1	37	rs374267184	I287F	DEL	0.001	Prob Dam	1
13	rs143059623	Y536C	DEL	0.003	Prob Dam	0.999	38	rs147882384	N98S	DEL	0.012	Prob Dam	0.999
14	rs144367585	M731T	DEL	0.009	Possibly Dam	0.464	39	rs374979020	R883C	DEL	0	Prob Dam	1
15	rs145610471	F777L	DEL	0.01	Prob Dam	0.921	40	rs375640530	Y636C	DEL	0.011	Prob Dam	0.996
16	rs141331151	P371S	DEL	0.01	Prob Dam	0.994	41	rs375983592	R959W	DEL	0	Prob Dam	1
17	rs139921635	P513T	DEL	0.01	Prob Dam	1	42	rs377163219	R576L	DEL	0	Prob Dam	1
18	rs149118364	R943H	DEL	0.03	BENIGN	0.067	43	rs377294345	R954H	DEL	0.02	Prob Dam	1
19	rs150168072	R572C	DEL	0.001	Prob Dam	1	44	rs201820778	R1053C	DEL	0.038	Prob Dam	1
20	rs201524333	S1038F	DEL	0.021	BENIGN	0.368	45	rs374977549	P510A	DEL	0.054	Prob Dam	1
21	rs202031187	G374S	DEL	0.005	Prob Dam	1	46	rs200161568	D791V	DEL	0.021	Prob Dam	0.908
22	rs202136117	D815Y	DEL	0.008	Prob Dam	0.767	47	rs188256169	P77T	DEL	0.022	BENIGN	0.003
23	rs202230275	R94Q	DEL	0.008	Prob Dam	0.897	48	rs150652042	R137W	DEL	0.032	BENIGN	0
24	rs367831484	G983S	DEL	0.02	Prob Dam	1	49	rs150012152	G412S	DEL	0.02	Prob Dam	1
25	rs368865428	C567R	DEL	0	Prob Dam	1	50	rs149726955	L801F	DEL	0.004	Prob Dam	1

Threshold: SIFT: < 0.05 PolyPhen-2: Probably Damaging: score > 0.908; Possibly Damaging: 0.446 < score ≤ 0.908; Benign: score ≤ 0.446