Table 3.
Confirmation of highly deleterious nsSNPs by other prediction software
A.A position | PROVEAN | FATHMM | LRT | M-CAP | MetaSVM | MetaLR | Mutation Assessor | MutationTaster | FATHMM MKL Coding | CADD | PhD-SNP | PANTHER | SNPs&GO | PON-P2 | DANN | SNAP2 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G298R | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
C567Y | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
A370T | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
C567R | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
G374S | D | D | D | D | D | D | D | D | D | D | N | D | D | D | D | D |
G983S | D | T | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
R435H | D | D | D | D | D | D | D | D | D | D | N | D | D | D | D | D |
Q616H | D | T | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
I291T | D | T | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
T668M | D | T | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
R572C | D | T | D | D | D | T | D | D | D | D | D | D | D | D | D | D |
R576L | D | T | D | D | D | D | D | D | D | D | D | D | D | D | D | D |
S58F | D | T | D | D | D | D | D | D | D | D | D | D | N | D | D | D |
R565W | D | T | D | D | D | T | D | D | D | D | D | D | D | D | D | D |
A336V | D | D | D | D | D | D | D | D | D | D | N | D | N | D | D | D |
R959W | D | T | D | D | D | D | D | D | D | D | N | D | D | D | D | D |
G412S | D | D | D | D | D | D | T | D | D | D | N | D | D | D | D | D |
P371S | D | D | D | D | D | D | D | D | D | D | N | D | D | U | D | D |
R883C | D | T | D | D | D | T | D | D | D | D | N | D | D | D | D | D |
Y636C | D | T | T | D | D | D | D | T | D | D | D | D | D | D | D | D |
Y536C | D | T | D | D | T | T | D | D | D | D | D | D | D | D | D | D |
R954H | D | T | D | D | D | T | D | D | D | D | D | D | D | U | D | D |