Table 1.
Patient characteristics
| All Patients (n = 215) |
COA with BAV (n = 145) |
COA with TAV (n = 70) |
p value | |
|---|---|---|---|---|
| Age, years | 25.3 (18.8, 34.3) | 25.7 (1.3,34.3) | 24.5 (17.7, 34.3) | 0.75 |
| Gender, male, n (%) | 121 (56) | 85 (59) | 36 (51) | 0.38 |
| BSA, m2 | 1.8 (1.6, 2) | 1.8 (1.6, 2) | 1.8 (1.6, 2) | 0.89 |
| Type of BAV, n (%) | ||||
| Left-right fusion | 125 (86) | |||
| Right-non fusion | 17 (12) | |||
| Left-non fusion | 3 (2) | |||
| Age at COA treatment, years | 1.7(0.1, 6.9) | 1.1(0.1, 1.1) | 2.4 (0.1, 10.2) | 0.37 |
| Treatment modality, n (%) | 0.72 | |||
| Surgery | 183 (85) | 125 (86) | 58 (84) | |
| Balloon dilation | 18 (8) | 12 (8) | 6 (9) | |
| Stent | 14 (7) | 8 (6) | 6 (9) | |
| Type of surgical repair, n (%) | 0.37 | |||
| End-to-end repair | 107 (59) | 77 (62) | 30 (51) | |
| Subclavian flap | 25 (14) | 15 (12) | 10 (17) | |
| Patch reconstruction | 13 (7) | 6 (5) | 7 (12) | |
| Interposition graft | 8 (4) | 5 (4) | 3 (5) | |
| Extended end-to-end repair | 1 (0.5) | 1 (1) | 0 | |
| Unavailable surgical record* | 29 (16) | 21 (17) | 8 (14) | |
| > Mild aortic regurgitation, n (%) | 11(5) | 11 (8) | 0 | 0.02 |
| > Mild aortic stenosis, n (%) | 7 (3) | 7 (5) | 0 | 0.10 |
| Medication use, n (%) | ||||
| β-blocker | 33 (16) | 18 (12) | 15 (21) | 0.11 |
| ACE inhibitor | 43 (20) | 28 (19) | 15 (21) | 0.72 |
| Hydrochlorothiazide | 10 (5) | 9 (6) | 1 (1) | 0.17 |
| Angiotensin receptor blocker | 9 (4) | 9 (6) | 0 | 0.03 |
| Calcium channel blocker | 8 (4) | 5 (3) | 3 (4) | 0.72 |
Data are presented as number (percent) or median (IQR range)
BSA body surface area, BAV bicuspid aortic valve, COA Coarctation of the aorta, ACE angiotensin-converting enzyme, TAV tricuspid aortic valve
*In a minority of patients whose initial surgical repair was at another institution, surgical records were not available to confirm details