Table 1.
Participant Characteristics by OSA–Hypopnea Index (OAHI) Categories: The ARIC Study, 1996-1998
| Participant Characteristics | OSA Category |
P for Difference | |||
|---|---|---|---|---|---|
| Normal |
Mild |
Moderate |
Severe |
||
| < 5 Events/h | 5-14 Events/h | 15-29 Events/h | ≥ 30 Events/h | ||
| No. | 814 | 475 | 202 | 95 | |
| OAHI median, events/h | 1.8 | 8.4 | 19.9 | 43.9 | |
| Demographics | |||||
| Age, y | 61.9 ± 5.5 | 63.4 ± 5.3 | 63.5 ± 5.4 | 63.9 ± 5.4 | < .0001 |
| Male, No. (%) | 286 (35.1) | 260 (54.7) | 141 (69.8) | 61 (64.2) | < .0001 |
| Education, No. (%) | .20 | ||||
| Less than high school diploma | 72 (8.9) | 61 (12.8) | 27 (13.4) | 8 (8.4) | |
| High school graduate | 389 (47.8) | 218 (45.9) | 88 (43.6) | 50 (52.6) | |
| Some college/ graduate school | 353 (43.4) | 196 (41.3) | 87 (43.1) | 37 (39.0) | |
| Behavioral characteristics | |||||
| Drinking status, No. (%) | .37 | ||||
| Current | 568 (69.8) | 323 (68.0) | 125 (61.9) | 62 (65.3) | |
| Former | 158 (19.4) | 104 (21.9) | 53 (26.2) | 20 (21.1) | |
| Never | 88 (10.8) | 48 (10.1) | 24 (11.9) | 13 (13.7) | |
| Smoking status, No. (%) | .001 | ||||
| Current | 110 (13.5) | 31 (6.5) | 14 (6.9) | 7 (7.4) | |
| Former | 360 (44.2) | 245 (51.6) | 110 (54.5) | 50 (52.6) | |
| Never | 344 (42.3) | 199 (41.9) | 78 (38.6) | 38 (40.0) | |
| Sport index | 2.7 ± 0.8 | 2.7 ± 0.8 | 2.6 ± 0.8 | 2.5 ± 0.7 | .06 |
| Physiologic characteristics | |||||
| BMI | 27.3 ± 4.4 | 29.4 ± 4.9 | 31.4 ± 5.5 | 34.0 ± 5.4 | < .0001 |
| C-reactive protein, mg/La | 2.1 (3.5) | 2.2 (3.6) | 2.1 (3.6) | 4.0 (6.4) | .001 |
| Prevalent asthma, No. (%) | 51 (6.3) | 31 (6.5) | 20 (9.9) | 5 (5.3) | .28 |
| Prevalent COPD, No. (%) | 6 (0.7) | 4 (0.8) | 2 (1.0) | 0 (0) | … |
| Prevalent CVD, No. (%) | 84 (10.3) | 54 (11.4) | 29 (14.4) | 18 (19.0) | .05 |
| Prevalent diabetes, No. (%) | 65 (8.0) | 73 (15.4) | 27 (13.4) | 20 (21.1) | < .0001 |
| eGFR, mL/min/1.73 m2 | 86.6 ± 14.2 | 84.2 ± 15.1 | 83.8 ± 14.6 | 78.7 ± 17.1 | < .0001 |
| < 60 | 40 (4.9) | 33 (7.0) | 14 (6.9) | 9 (9.5) | .005 |
| 60-89 | 408 (50.1) | 253 (53.3) | 114 (56.4) | 62 (65.3) | |
| ➢ 90 | 366 (45.0) | 189 (39.8) | 74 (36.6) | 24 (25.3) | |
Data are shown as No. (percentage) for categorical variables and as mean ± SD for continuous variables. CVD = cardiovascular disease; eGFR = estimated glomerular filtration rate.
a
Data are shown as median (interquartile range) for C-reactive protein because of skewness.