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. 2023 May 24;11(3):e02742-22. doi: 10.1128/spectrum.02742-22

TABLE 4.

Conidial viability parameters after 96 h of exposure to fermented C. subternata extracta

Fusarium strain % ATP production
IC50 of ATP (mg/mL)
Control Fermented C. subternata extract
AmpB (2.5 mg/mL)
20 mg/mL 10 mg/mL 5 mg/mL 2.5 mg/mL 1.25 mg/mL 0.62 mg/mL
F. verticillioides
 MRC 826-E 100 ± 0.67 8.40 ± 1.02*** 15.8 ± 1.34*** 47.0 ± 4.34*** 76.0 ± 2.84*** 80.8 ± 4.14*** 91.4 ± 1.82*** 50.1 ± 4.3*** 4.28 ± 0.31**
 MRC 826-J 100 ± 1.11 20.6 ± 1.88*** 26.6 ± 1.03** 29.9 ± 0.71*** 37.8 ± 2.26*** 62.2 ± 1.08*** 77.5 ± 2.66*** 23.3 ± 5.3*** 2.11 ± 0.06**
 MRC 8559 100 ± 1.35 17.2 ± 1.74*** 24.3 ± 1.91*** 30.5 ± 2.33*** 62.7 ± 0.68*** 73.0 ± 2.10*** 88.2 ± 1.71*** 2.08 ± 0.2*** 3.37 ± 0.13**
F. subglutinans
 MRC 8554 100 ± 5.00 6.04 ± 0.30*** 11.4 ± 0.45*** 130.9 ± 3.0*** 146.7 ± 7.9*** 223.5 ± 20*** 235.3 ± 21*** 1.77 ± 0.3*** 9.47 ± 0.13**
 MRC 8553 100 ± 2.11 3.79 ± 0.48*** 7.97 ± 0.12*** 84.1 ± 0.96*** 109.2 ± 2.4*** 178.5 ± 23*** 230.2 ± 17*** 3.51 ± 0.1*** 6.63 ± 0.06**
F. proliferatum
 MRC 8550 100 ± 3.19 6.04 ± 0.53*** 13.5 ± 0.78*** 20.7 ± 1.70*** 46.8 ± 2.88*** 61.3 ± 3.65*** 67.9 ± 2.58*** 44.1 ± 4.1*** 1.75 ± 0.21**
 MRC 8549 100 ± 3.34 9.73 ± 0.71*** 13.7 ± 1.48*** 24.0 ± 3.45*** 39.8 ± 1.67*** 48.4 ± 2.03*** 60.9 ± 2.11*** 45.2 ± 1.2*** 1.20 ± 0.05**
 
F. graminearum MRC 4927 100 ± 1.95 20.3 ± 1.12*** 42.1 ± 1.78*** 51.7 ± 2.30*** 58.6 ± 1.57*** 68.5 ± 2.34*** 77.3 ± 1.90*** 0.21 ± 0.0*** 4.49 ± 0.14**
F. globosum
 MRC 6647 100 ± 2.84 15.1 ± 1.92*** 25.2 ± 0.91*** 26.5 ± 0.90*** 52.5 ± 3.13*** 71.9 ± 1.58*** 77.7 ± 1.40*** 27.1 ± 4.2*** 2.62 ± 0.10**
 MRC 6122 100 ± 1.99 11.3 ± 1.45*** 17.0 ± 1.42*** 21.1 ± 1.25*** 33.6 ± 0.90*** 40.5 ± 1.63*** 47.7 ± 1.80*** 24.5 ± 2.7*** 0.70 ± 0.04**
a

Values represent means ± standard deviations of five replications from at least two experiments. % ATP production, percentage of spore viability of cell energy production; IC50 of ATP, MIC at 50% ATP; *** and **, statistically significant at P < 0.0001, and P < 0.001, respectively.