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. 2023 May 24;11(3):e02742-22. doi: 10.1128/spectrum.02742-22

TABLE 6.

Conidia viability parameters after 96 h exposure to unfermented C. sinensis extracta

Fusarium strain % ATP production
IC50 of ATP (mg/mL)
Control Unfermented C. sinensis extract
AmpB (2.5 mg/mL)
20 mg/mL 10 mg/mL 5 mg/mL 2.5 mg/mL 1.25 mg/mL 0.62 mg/mL
F. verticillioides
 MRC 826-E 100 ± 0.67 56.4 ± 1.38*** 122.6 ± 9.7*** 150.0 ± 4.1*** 160.6 ± 6.7*** 176.9 ± 15.4*** 196.0 ± 8.7*** 50.1 ± 4.3*** 0.00 ± 0.00**
 MRC 826-J 100 ± 1.11 27.5 ± 1.29*** 31.7 ± 1.07*** 46.5 ± 2.86*** 53.4 ± 1.37*** 65.9 ± 1.03*** 78.0 ± 1.17*** 23.3 ± 5.3*** 3.67 ± 0.21**
 MRC 8559 100 ± 1.35 51.2 ± 1.48*** 51.6 ± 1.51*** 60.7 ± 2.48*** 174.6 ± 17.6*** 188.2 ± 8.7*** 205.6 ± 12.3*** 2.08 ± 0.2*** 14.90 ± 0.46**
F. subglutinans
 MRC 8554 100 ± 5.00 121.5 ± 2.7*** 291.6 ± 9.1*** 399.9 ± 33.4*** 406.7 ± 19.6*** 439.4 ± 11.5*** 480.9 ± 17.7*** 1.77 ± 0.3*** 0.00 ± 0.00**
 MRC 8553 100 ± 2.11 77.2 ± 1.28*** 94.7 ± 5.64*** 115.1 ± 5.7*** 168.8 ± 16.8*** 188.2 ± 8.0*** 241.2 ± 17.2*** 3.51 ± 0.1*** 27.40 ± 3.19**
F. proliferatum
 MRC 8550 100 ± 3.19 52.7 ± 2.48*** 65.9 ± 6.23*** 68.3 ± 4.59*** 57.0 ± 8.58*** 109.4 ± 15.5*** 101.9 ± 1.0*** 44.1 ± 4.1*** 18.36 ± 5.36**
 MRC 8549 100 ± 3.34 47.0 ± 1.52*** 54.8 ± 2.28*** 55.5 ± 2.27*** 57.6 ± 2.48*** 63.6 ± 2.14*** 87.2 ± 1.03*** 45.2 ± 1.2*** 11.25 ± 1.42**
 
F. graminearum MRC 4927 100 ± 1.95 59.9 ± 2.25*** 97.1 ± 15.1*** 124.9 ± 3.3*** 139.6 ± 3.6*** 190.3 ± 15.0*** 213.0 ± 17.3*** 0.21 ± 0.0*** 22.19 ± 0.93**
F. globosum
 MRC 6647 100 ± 2.84 25.0 ± 2.84*** 42.8 ± 2.19*** 61.7 ± 2.46*** 120.7 ± 1.4*** 139.6 ± 2.3*** 161.2 ± 13.9*** 27.1 ± 4.2*** 9.26 ± 0.65**
 MRC 6122 100 ± 1.99 43.9 ± 1.72*** 59.6 ± 1.25*** 80.6 ± 1.08*** 87.8 ± 6.00*** 93.8 ± 2.31*** 103.8 ± 5.7*** 24.5 ± 2.7*** 15.23 ± 0.81**
a

Values represent means ± standard deviations of five replications from at least two experiments. % ATP production, percentage of spore viability of cell energy production; IC50 of ATP, MIC at 50% ATP; *** and **, statistically significant at P < 0.0001 and P < 0.001, respectively.