Probio-X improved blood lipid indexes in hyperlipidemia patients. (A) Comparative analysis of (A) blood indicators; (B) body weight and composition; (C) gut mucosa indicators. (D) Number of patients that were responsive toward probiotic treatment, evaluated by changes in four key blood lipid indicators. Chi-square test was performed to evaluate the overall difference between two groups. LDL-C, low-density lipoprotein; TC, total cholesterol; HDL-C, high-density lipoprotein; TG, triglyceride; *, P < 0.05; **, P < 0.01; ***, P < 0.001 (t test). Pla_0M and Pla_3M indicate before and 3 months after the placebo intervention, respectively, and Pro_0M and Pro_3M before and 3 months after the probiotic intervention, respectively.