TABLE 5.
Reproducibility of BioCode RPPa
| Pathogen | No. of samples detected/tested (% agreement) by site and test |
Total no. of samples detected/tested (%) (95% CI) | ||
|---|---|---|---|---|
| Site 1, easyMAG | Site 2, MagNA Pure | Site 3, easyMAG | ||
| Adenovirus | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Coronavirus NL63 | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Human metapneumovirus | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Human rhinovirus/enterovirus | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Influenza A H3b | 59/60 (98.3) | 60/60 (100) | 60/60 (100) | 179/180 (99.4) (96.9–99.9) |
| Influenza Bb | 59/60 (98.3) | 60/60 (100) | 60/60 (100) | 179/180 (99.4) (96.9–99.9) |
| Parainfluenza virus 2 | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Parainfluenza virus 3 | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Respiratory syncytial virusb,c | 58/60 (96.7) | 60/60 (100) | 60/60 (100) | 178/180 (98.9) (96.0–99.7) |
| Bordetella pertussis | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Chlamydia pneumoniae | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
| Mycoplasma pneumoniae | 60/60 (100) | 60/60 (100) | 60/60 (100) | 180/180 (100) (97.9–100.0) |
a
Reproducibility was assessed with a panel of samples at 3 different sites, 2 with easyMAG and 1 with MagNA Pure 96 extraction systems.
b
Low positive, 1.5 times LoD not detected.
c
Medium positive, 3 times LoD not detected.