TABLE 1.
VL-diagnostic performance of rKLd8.3, rKLa8.3, and rKLi8.3 ELISA in Sudana
| ELISA test | Cutoff | AUC | TP | FN | TN | FP | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | DEV (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rKLd8.3 | 0.124 | 0.9894 | 164 | 8 | 125 | 1 | 95.35 | 99.20 | 99.39 | 93.98 | 96.97 |
| rKLa8.3 | 0.097 | 0.9947 | 166 | 6 | 125 | 1 | 96.51 | 99.20 | 99.40 | 95.41 | 97.65 |
| rKLi8.3 | 0.106 | 0.9956 | 167 | 5 | 125 | 1 | 97.10 | 99.20 | 99.40 | 96.15 | 97.98 |
a
AUC, area under the curve; DEV, diagnostic efficiency value; ELISA, enzyme-linked immunosorbent assay; FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive; VL, visceral leishmaniasis.