TABLE 2.
VL-diagnostic performance of rKLi6.3, rKLi7.3, and rKLi8.3 ELISA in Sudana
ELISA test | Cutoff | AUC | TP | FN | TN | FP | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | DEV (%) |
---|---|---|---|---|---|---|---|---|---|---|---|
rKLi6.3 | 0.112 | 0.9881 | 159 | 13 | 122 | 4 | 92.44 | 96.82 | 97.54 | 90.37 | 94.29 |
rKLi7.3 | 0.101 | 0.9892 | 162 | 10 | 124 | 2 | 94.18 | 98.41 | 98.78 | 92.54 | 95.97 |
rKLi8.3 | 0.106 | 0.9959 | 167 | 5 | 125 | 1 | 97.10 | 99.20 | 99.40 | 96.15 | 97.98 |
AUC, area under the curve; DEV, diagnostic efficiency value; ELISA, enzyme-linked immunosorbent assay; FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive; VL, visceral leishmaniasis.