TABLE 3.
VL-diagnostic performance of rK39, rKLO8, and rKLi8.3 ELISA in Sudana
| ELISA test | Cutoff | AUC | TP | FN | TN | FP | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | DEV (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rK39 | 0.146 | 0.9687 | 157 | 15 | 118 | 8 | 91.28 | 93.65 | 95.15 | 88.72 | 92.28 |
| rKLO8 | 0.120 | 0.9862 | 159 | 13 | 123 | 3 | 92.44 | 97.62 | 98.15 | 90.44 | 94.63 |
| rKLi8.3 | 0.106 | 0.9920 | 167 | 5 | 125 | 1 | 97.10 | 99.20 | 99.40 | 96.15 | 97.98 |
a
AUC, area under the curve; DEV, diagnostic efficiency value; ELISA, enzyme-linked immunosorbent assay; FN, false negative; FP, false positive; NPV, negative predictive value; PPV, positive predictive value; TN, true negative; TP, true positive; VL, visceral leishmaniasis.