TABLE 4.
Diagnostic performance of commercial ELISA (TECAN, NovaLisa) and rKLi8.3 prototype ELISAa
ELISA test | Cutoff | AUC | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | DEV (%) |
---|---|---|---|---|---|---|---|
TECAN | 11 U | 0.7670 | 50.0 | 81.81 | 50.0 | 81.81 | 73.33 |
NovaLisa | 11 U | 0.7784 | 50.0 | 72.72 | 40.0 | 80.0 | 66.66 |
rKLi8.3 | 11 U | 0.9219 | 75.0 | 95.45 | 85.71 | 91.30 | 90.0 |
AUC, area under the curve; DEV, diagnostic efficiency value; ELISA, enzyme-linked immunosorbent assay; NPV, negative predictive value; PPV, positive predictive value.