TABLE 2.
Overall median CD4 among HIV-positive and HIV-negative individuals (excluding Uganda), reported by age group from aggregate data in 11 population-based HIV impact assessment (PHIA) countries as well as by detectable antiretrovirals (ARV) and undetectable ARVsa
Ageb (yrs) | HIV negativec (n = 7,329) |
HIV positived |
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---|---|---|---|---|---|---|---|---|---|
n | Median (Q1, Q3) | Total (n = 22,892) |
Detectable ARVs (n = 15,439) |
Non-detectable ARVs (n = 7,453) |
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n | Median (Q1, Q3) | n | Median (Q1, Q3) | n | Median (Q1, Q3) | P valuee | |||
0 to 5 | 983 | 1,470 (1,104, 1,938) | 163 | 995 (665, 1,418) | 83 | 1,071 (689, 1,513) | 80 | 857 (640, 1,271) | 0.0229 |
6 to 14 | 1,140 | 999 (797, 1,267) | 476 | 772.5 (527, 1,108) | 323 | 884 (587, 1,192) | 153 | 596 (413, 824) | <0.0001 |
15 to 29 | 2,659 | 830 (662, 1,025) | 4,919 | 508 (344, 706) | 2,538 | 580 (406, 771) | 2,381 | 441 (295, 618) | <0.0001 |
30 to 44 | 1,455 | 807 (656, 1,006) | 10,737 | 461 (299, 642) | 7,394 | 505 (347, 678) | 3,343 | 359 (223, 529) | <0.0001 |
45+ | 1,092 | 776.5 (596, 988) | 6,597 | 451 (295, 634) | 5,101 | 478 (326, 654) | 1,496 | 352 (211, 531.5) | <0.0001 |
0 to 14 | 2,123 | 1,171 (885, 1,580) | 639 | 823 (561, 1,171) | 406 | 914 (615, 1,244) | 233 | 675 (465, 951) | <0.0001 |
15+ | 5,206 | 811 (647, 1,013) | 22,253 | 468 (307, 654) | 15,033 | 508 (349, 686) | 7,220 | 385.5 (242, 563.5) | <0.0001 |
All of the CD4 data are unweighted. Abbreviations: Q1, first quartile; Q3, third quartile.
The eligible age-range to participate in the PHIA study was 0 to 64 years in Cameroon, Côte d’Ivoire, Ethiopia, Malawi, Namibia, Zimbabwe and Uganda; 0 to 59 years in Zambia and Lesotho; and 15+ years in Eswatini and Tanzania.
Excludes Uganda. CD4 cell count measurements for participants who tested HIV-negative were not part of the protocol.
The HIV-positive participants with missing ARV measurements (n = 193) were excluded from analysis.
The Wilcoxon P values are among the HIV-positive groups, comparing detectable and undetectable ARVs.