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. 2023 Apr 12;11(3):e05066-22. doi: 10.1128/spectrum.05066-22

TABLE 1.

Risk factors for short-term survival

Characteristics OR (95% CI)a
Crude risk Adjusted risk
Model 1 Model 2
Patient characteristics at surgery
 Age, yrs
  <60 1.00 (ref) 1.00 (ref) 1.00 (ref)
  60–69 0.87 (0.24–3.09) 2.45 (0.26–22.72) 2.59 (0.28–24.38)
  70−74 2.40 (0.65–8.81) 12.55 (1.06–149.26) 14.24 (1.21–167.40)
  ≥75 1.96 (0.56–6.91) 8.68 (0.79–95.19) 10.55 (0.99–112.75)
 Sex
  Female 1.00 (ref) 1.00 (ref) 1.00 (ref)
  Male 0.76 (0.35–1.67) 0.47 (0.14–1.56) 0.44 (0.13–1.41)
 ASA score
  I (healthy) 1.00 (ref) 1.00 (ref) 1.00 (ref)
  II (mild) 0.80 (0.32–2.02) 2.29 (0.45–11.78) 2.69 (0.56–12.96)
  III-IV (severe or worse) 2.01 (0.65–6.19) 4.10 (0.60–27.92) 4.99 (0.79–31.45)
 Preoperative treatment
  None 1.00 (ref) 1.00 (ref)
  Radiotherapy 1.17 (0.74–1.84) 0.71 (0.12–4.15)
Tumor characteristics
 Localization
  Colon right 1.00 (ref) 1.00 (ref) 1.00 (ref)
  Colon left 0.47 (0.16–1.32) 0.78 (0.16–3.82) 0.76 (0.16–3.63)
  Rectum 0.72 (0.28–1.84) 2.03 (0.33–12.63) 1.61 (0.36–7.21)
 Mucinous cancer
  No 1.00 (ref) 1.00 (ref)
  Yes 0.83 (0.24–2.93) 0.50 (0.05–5.39)
 TNM stage
  III 1.00 (ref) 1.00 (ref) 1.00 (ref)
  IV 10.8 (3.68–31.72) 44.67 (5.53–360.63) 49.32 (5.86–415.12)
 Grade of differentiation
  Low 1.00 (ref) 1.00 (ref) 1.00 (ref)
  Medium 0.20 (0.07–0.54) 0.23 (0.05–0.98) 0.24 (0.06–1.00)
  High 0.21 (0.05–0.97) 0.09 (0.01–1.24) 0.10 (0.01–1.27)
Surgical characteristics
 Period of surgery
  1997−2005 1.00 (ref) 1.00 (ref) 1.00 (ref)
  2006−2010 0.54 (0.21–1.37) 0.44 (0.10–1.92) 0.44 (0.10–1.89)
  2011−2017 0.59 (0.21–1.65) 1.19 (0.22–6.47) 1.08 (0.22–5.36)
 Radical operation
  No 1.00 (ref) 1.00 (ref) 1.00 (ref)
  Yes 0.05 (0.01–0.41) 0.13 (0.01–1.51) 0.12 (0.01–1.34)
a

Model 1 values are adjusted for all variables. Model 2 values are adjusted for all variables except for preoperative treatment and mucinous cancer. ref, reference.