TABLE 2.
RSV single versus co-infections
| Population | Single RSV infection |
RSV co-infection |
|||
|---|---|---|---|---|---|
| N (%) | N (%) | ||||
| n | 63 | n | 47 | P | |
| General characteristicsb | |||||
| Male sex (n, %) | 32 | 63 (50.8) | 36 | 47 (76.6) | 0.01 c |
| Prematurity (n, %) | 8 | 63 (12.7) | 3 | 47 (6.4) | 0.35 |
| Small for gestational age (n, %) | 6 | 62a (9.7) | 4 | 47 (8.5) | 1 |
| Daycare attendance (n, %) | 24 | 62a (38.7) | 32 | 43a (74.4) | <0.001 |
| Breast feeding (n, %) | 40 | 63 (63.5) | 25 | 47 (53.2) | 0.28 |
| Parental atopy (n, %) | 6 | 61a (9.8) | 12 | 44a (27.3) | 0.02 |
| Parental smoking (n, %) | 12 | 59a (20.3) | 17 | 44a (38.6) | 0.04 |
| Age | 3.3 | 1.6-8.8 | 5.8 | 3.9 to 11.2 | 0.03 |
| Clinical parameters | |||||
| Dyspnea (n, %) | 43 | 63 (68.3) | 39 | 47 (83) | 0.08 |
| Anorexia (n, %) | 51 | 63 (81) | 38 | 47 (80.9) | 0.99 |
| Fever (n, %) | 50 | 63 (79.4) | 40 | 47 (85.1) | 0.44 |
| Cyanosis (n, %) | 3 | 63 (4.8) | 2 | 47 (4.3) | 1 |
| Tachypnea on admission (n, %) | 42 | 63 (66.7) | 28 | 47 (59.6) | 0.44 |
| Tachycardia on admission (n, %) | 20 | 63 (32.3) | 13 | 47 (27.7) | 0.61 |
| Primary outcome measuresd | |||||
| PICU admission (n, %) | 17 | 63 (27) | 3 | 47 (6.4) | 0.01 |
| Duration of hospitalization (days, median, Q1 to Q3) | 4 | 3 to 7 | 3 | 2 to 5 | 0.02 |
| Desaturation on admission (n, %) | 17 | 63 (27) | 8 | 47 (17) | 0.22 |
| O2 administration (n, %) | 41 | 63 (65.1) | 24 | 47 (51.1) | 0.14 |
| BRAS (median, Q1 to Q3) | 3 | 2 to 4 | 2 | 1 to 3 | 0.01 |
| Secondary outcome measures | |||||
| Duration of O2 administration (days; median, Q1 to Q3) | 3 | 1.5 to 5 | 2 | 1 to 4.875 | 0.49 |
| Maximum O2 flow (l/min; median, Q1 to Q3) | 8 | 1 to 12.5 | 1.5 | 1 to 14 | 0.73 |
| Maximum FiO2 (%, median Q1 to Q3) | 28 | 24 to 47 | 24 | 24 to 30 | 0.16 |
| Intubation (n, %) | 3 | 63 (4.8) | 0 | 47 (0) | 0.26 |
| ReSVinet score (median, Q1 to Q3) | 9 | 5 to 12 | 8 | 5 to 11 | 0.43 |
a
Data are lacking for some patients.
b
Statistical analysis was performed using Pearson's chi-squared, Fisher’s exact, or Mann-Whitney-U test, as appropriate.
c
Significant P-values in bold.
d
PICU, pediatric intensive care unit; BRAS, Bronchiolitis Risk of Admission Score; FiO2, fraction of inspired oxygen; .