Table 5.
Clinical outcomes analysis in CVP dropped to less than 13.46 mmHg and group whose CVP did not drop to less than 13.46 mmHg.
| Outcomes | Second day CVP ≤ 13.46 mmHg | Second day CVP > 13.46 mmHg | p-value |
|---|---|---|---|
| Primary outcome | |||
| 28-day mortality | 10/275 (3.64) | 33/372 (8.87) | 0.010** |
| Secondary outcomes | |||
| In-hospital mortality | 9/ 275 (3.27) | 38/372 (10.22) | <0.001*** |
| 1-year mortality | 11/ 275 (4.00) | 50/372 (13.44) | <0.001*** |
| Length of ICU stay (days) | 3.28 (2.14–5.22) | 4.33 (2.63–8.87) | <0.001*** |
| Length of hospitalization (days) | 9.43 (6.39–14.47) | 11.77 (7.67–17.73) | <0.001*** |
| AKI within 7 days, n (%) | 111/ 275 (40.36) | 228/372 (61.29) | <0.001*** |
| RRT, n (%) | 11/ 275 (4.00) | 49/372 (13.17) | <0.001*** |
| Vasopressor, n (%) | 263/ 275 (95.64) | 363/372 (97.58) | 0.1837 |
| Maximum of lactate level on day 2 (mmol/L) | 1.80 (0.08) | 2.63 (0.16) | <0.001*** |
| Lactate clearance on day 2 (%) | 4.59 (2.77) | 4.62 (2.85) | 0.994 |
| Duration of ventilation (h) | 16.83 (7.60–29.98) | 29.38 (14.25–104.62) | <0.001*** |
| PO2/FiO2 (mmHg) | 160 (106–221) | 148 (104–107) | 0.047* |
| Fluid balance on day 1 (L) | 10.32 (0.33) | 12.49 (0.31) | <0.001*** |
| Fluid balance on day 2 (L) | 1.08 (0.18) | 3.08 (0.23) | <0.001*** |
CVP, central venous pressure; ICU, intensive care unit; AKI, acute kidney injury; RRT, renal replacement therapy; PO2, partial pressure of oxygen; FiO2, fraction of inspiration oxygen.
*p<0.05; **p<0.01; ***p<0.001.