Table 2.

Results of linear mixed‐effects models including APOE.

Aβ species	Aβ40				Aβ42				Aβ40/42 ratio
Linear mixed‐effects models including APOE
Model includes	APOE‐ε4		APOE‐ε2		APOE‐ε4		APOE‐ε2		APOE‐ε4		APOE‐ε2
Fixed effect	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P	β (SE)	P
Intercept	101.10 (2.45)	<0.001	101.15 (2.38)	<0.001	13.14 (0.35)	<0.001	13.19 (0.34)	<0.001	7.67 (0.19)	<0.001	7.60 (0.18)	<0.001
Age	0.35 (0.03)	<0.001	0.34 (0.02)	<0.001	0.02 (0.004)	<0.001	0.01 (0.003)	>0.001	0.02 (0.002)	<0.001	0.02 (0.002)	<0.001
APOE	−0.12 (2.88)	0.966	−2.45 (4.26)	0.566	0.39 (0.38)	0.312	−0.13 (0.57)	0.826	−0.40 (0.19)	0.037	−0.03 (0.29)	0.913
eGFR	−0.22 (0.02)	<0.001	−0.22 (0.02)	<0.001	−0.03 (0.003)	<0.001	−0.03 (0.003)	<0.001	0.002 (0.001)	0.194	0.002 (0.001)	0.163
Age × APOE	−0.002 (0.05)	0.977	0.08 (0.08)	0.3041	−0.02 (0.01)	0.028	0.01 (0.01)	0.365	0.01 (0.004)	<0.001	−0.002 (0.01)	0.752

Aβ, amyloid‐beta; SE, standard error; eGFR, estimated glomerular filtration rate.

β is the fixed effect and P is the P‐value. “×” indicates an interaction between two variables.