Table 3.
Postnatal development of dendritic spines of striatonigral (dSPNs) and striatopallidal neurons (iSPNs) in subregions of the nucleus accumbens of male mice
| Age | NAcc | NAcsLat | NAcsMed |
|---|---|---|---|
| Striatonigral neurons/dSPNs | |||
| P13 | 8.356 ± 0.634 | 8.780 ± 0.803 | 10.222 ± 0.562 |
| P21 | 11.492 ± 0.685 | 9.772 ± 0.546 | 10.265 ± 0.712 |
| P30 | 10.359 ± 0.849# | 14.250 ± 0.596 | 11.852 ± 0.822 |
| P50 | 10.068 ± 1.087 | 10.884 ± 0.919 | 8.797 ± 0.486 |
| P100 | 8.700 ± 0.675# | 10.923 ± 0.474 | 8.461 ± 1.215# |
| Striatopallidal neurons/iSPNs | |||
| P13 | 8.657 ± 0.616 | 9.501 ± 0.557 | 8.792 ± 0.825 |
| P21 | 8.843 ± 0.878* | 10.539 ± 0.681** | 7.876 ± 0.659 |
| P30 | 10.860 ± 0.587 | 11.990 ± 0.536 | 8.495 ± 0.699 |
| P50 | 10.979 ± 0.857 | 10.861 ± 0.764 | 10.019 ± 0.613 |
| P100 | 8.137 ± 0.816 | 9.681 ± 0.575 | 8.618 ± 0.395 |
The numbers indicate the density of dendritic spines (mean ± SEM) on different postnatal days (P). # versus NAcsLat, #p < 0.05. * versus NAcsMed, *p < 0.05, **p < 0.01. NAcc: nucleus accumbens core; NAcsLat: lateral part of nucleus accumbens shell; NAcsMed: medial part of nucleus accumbens shell.