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. 2023 Jun 16;102(24):e34017. doi: 10.1097/MD.0000000000034017

Table 2.

Comparison of demographic and clinicopathologic characteristics of noncarriers and carriers of the SERPINA5 p.E228Q variant from our combined discovery and validation cohorts.

Characteristic SERPINA5 p.E228Q Overall P value
Carriers (n = 6) noncarriers (n = 1211)
Age at death, yr 79 (74, 85) 81 (75, 87) .682
Age at onset, yr 66 (60, 73) 71 (63, 77) .351
Disease duration, yr 12 (10, 15) 9 (6, 12) .079
Braak tangle stage VI (IV, VI) VI (V, VI) .978
Thal amyloid phase 5 (5, 5) 5 (5, 5) .266

Data shown as median (25th, 75th percentile). Statistical analysis was performed using the Mann-Whitney Rank Sum Test.

AD = Alzheimer’s disease.