Table 2.
Pooled risks of type 2 diabetes mellitus (T2DM; and 95 % confidence intervals) in association with ‘healthy’ dietary patterns in different subgroup analyses
| Meta-analysis | Heterogeneity | |||||||
|---|---|---|---|---|---|---|---|---|
| Subgroup | Category | No. of studies | No. of participants | OR | 95 % CI | I 2 (%) | P value | P value for between-subgroup heterogenity |
| Sex | Female | 2 | 76 145 | 0·86 | 0·77, 0·95 | 0·0 | 0·69 | 0·96 |
| Male | 3 | 106 576 | 0·86 | 0·80, 0·94 | 0·0 | 0·77 | ||
| Both | 8 | 184 882 | 0·86 | 0·79, 0·93 | 36·0 | 0·14 | ||
| Region | Western | 8 | 254 057 | 0·86 | 0·82, 0·91 | 0·0 | 0·81 | 0·68 |
| Eastern | 5 | 113 546 | 0·87 | 0·76, 1·00 | 48·5 | 0·10 | ||
| Overall quality score of study | High | 5 | 159 107 | 0·85 | 0·79, 0·90 | 0·0 | 0·87 | 0·60 |
| Low | 8 | 208 496 | 0·88 | 0·81, 0·94 | 31·3 | 0·17 | ||
| Follow-up years | ≥10 years | 9 | 261 100 | 0·86 | 0·80, 0·91 | 27·1 | 0·20 | 0·76 |
| <10 years | 4 | 106 503 | 0·87 | 0·79, 0·95 | 0·0 | 0·89 | ||
| Person-years | ≥100 000 | 3 | 116 362 | 0·85 | 0·77, 0·94 | 0·0 | 0·44 | 0·96 |
| <100 000 | 5 | 74 237 | 0·87 | 0·77, 0·99 | 57·1 | 0·05 | ||
| Adjustment for physical activity | Yes | 11 | 326 512 | 0·86 | 0·82, 0·90 | 3·4 | 0·41 | 0·31 |
| No | 2 | 41 091 | 0·76 | 0·60, 0·96 | 0·0 | 0·57 | ||
| Publication year | After 2010 | 8 | 208 496 | 0·87 | 0·81, 0·93 | 29·9 | 0·18 | 0·81 |
| Before 2010 | 5 | 159 107 | 0·85 | 0·79, 0·92 | 0·0 | 0·80 | ||
| Adjustment for family history of T2DM | Yes | 7 | 223 519 | 0·86 | 0·79, 0·93 | 0·0 | 0·81 | 0·96 |
| No | 6 | 144 084 | 0·87 | 0·80, 0·93 | 42·5 | 0·12 | ||
| Ethnic difference | Western | 5 | 173 534 | 0·88 | 0·80, 0·96 | 0·0 | 0·47 | 0·82 |
| Western-Japanese/Chinese | 3 | 80 523 | 0·85 | 0·80, 0·91 | 0·0 | 0·98 | ||
| Japanese/Chinese | 5 | 113 546 | 0·87 | 0·76, 1·00 | 48·5 | 0·10 | ||
| Adjustment for educational status | Yes | 3 | 95 897 | 0·87 | 0·81, 0·94 | 0·0 | 0·38 | 0·55 |
| No | 10 | 271 706 | 0·85 | 0·80, 0·90 | 4·6 | 0·39 | ||
| T2DM incidence | ≥1000 cases | 6 | 230 746 | 0·86 | 0·80, 0·92 | 2·8 | 0·23 | 0·82 |
| <1000 cases | 7 | 136 857 | 0·86 | 0·80, 0·93 | 0·0 | 0·58 | ||
| Health-care system employee participants | Yes | 6 | 219 215 | 0·87 | 0·80, 0·94 | 0·0 | 0·89 | 0·74 |
| No | 7 | 148 388 | 0·86 | 0·80, 0·92 | 39·6 | 0·12 | ||