Table 3.
Pooled risks of type 2 diabetes mellitus (T2DM; and 95 % confidence intervals) in association ‘unhealthy’ dietary patterns in different subgroup analyses
| Meta-analysis | Heterogeneity | |||||||
|---|---|---|---|---|---|---|---|---|
| Subgroup | Category | No. of studies | No. of participants | OR | 95 % CI | I 2 (%) | P value | P value for between-subgroup heterogenity |
| Sex | Female | 2 | 76 145 | 1·01 | 0·68, 1·51 | 84·3 | 0·01 | 0·02 |
| Male | 3 | 106 576 | 1·39 | 1·19, 1·62 | 53·1 | 0·11 | ||
| Both | 7 | 179 217 | 1·35 | 1·18, 1·53 | 52·5 | 0·05 | ||
| Region | Western | 8 | 254 057 | 1·38 | 1·26, 1·52 | 51·9 | 0·04 | 0·004 |
| Eastern | 4 | 107 881 | 1·07 | 0·86, 1·33 | 61·6 | 0·05 | ||
| Overall quality score of study | High | 5 | 159 107 | 1·40 | 1·26, 1·56 | 33·5 | 0·19 | 0·03 |
| Low | 7 | 202 831 | 1·21 | 1·04, 1·41 | 70·2 | 0·003 | ||
| Follow-up years | ≥10 years | 8 | 255 435 | 1·39 | 1·26, 1·52 | 40·7 | 0·11 | 0·001 |
| <10 years | 4 | 106 503 | 1·12 | 0·92, 1·38 | 63·7 | 0·04 | ||
| Person-years | ≥100 000 | 3 | 116 362 | 1·53 | 1·36, 1·71 | 0·0 | 0·87 | 0·003 |
| <100 000 | 4 | 68 572 | 1·25 | 1·06, 1·48 | 54·0 | 0·09 | ||
| Adjustment for physical activity | Yes | 10 | 320 847 | 1·27 | 1·15, 1·42 | 68·4 | 0·001 | 0·17 |
| No | 2 | 41 091 | 1·53 | 1·20, 1·97 | 0·0 | 0·72 | ||
| Publication year | After 2010 | 7 | 202 831 | 1·21 | 1·05, 1·40 | 66·6 | 0·006 | 0·22 |
| Before 2010 | 5 | 159 107 | 1·42 | 1·22, 1·66 | 63·9 | 0·03 | ||
| Adjustment for family history of T2DM | Yes | 6 | 217 854 | 1·32 | 1·08, 1·61 | 74·0 | 0·002 | 0·20 |
| No | 6 | 144 084 | 1·27 | 1·15, 1·41 | 47·9 | 0·09 | ||
| Ethnic difference | Western | 5 | 173 534 | 1·54 | 1·39, 1·70 | 0·0 | 0·98 | <0·001 |
| Western-Japanese/Chinese | 3 | 80 523 | 1·26 | 1·14, 1·40 | 50·3 | 0·13 | ||
| Japanese/Chinese | 4 | 107 881 | 1·07 | 0·86, 1·33 | 61·6 | 0·05 | ||
| Adjustment for educational status | Yes | 3 | 95 897 | 1·35 | 1·19, 1·53 | 42·6 | 0·17 | 0·36 |
| No | 9 | 266 041 | 1·27 | 1·11, 1·46 | 69·4 | 0·001 | ||
| T2DM incidence | ≥1000 cases | 6 | 230 746 | 1·36 | 1·22, 1·51 | 52·7 | 0·06 | 0·03 |
| <1000 cases | 6 | 131 192 | 1·24 | 1·04, 1·48 | 67·1 | 0·009 | ||
| Health-care system employee participants | Yes | 5 | 213 550 | 1·29 | 1·02, 1·63 | 78·8 | 0·001 | 0·34 |
| No | 7 | 18 388 | 1·29 | 1·17, 1·42 | 44·1 | 0·09 | ||