Table 2.
Crude associations between excess free fructose (EFF) beverage intakes and asthma prevalence in children aged 2–9 years, National Health and Nutrition Examination Survey (NHANES) 2003–2006
| % of consumers | 95 % CI | Asthma (% yes) | P value | |
|---|---|---|---|---|
| AJ* (n 1961) | ||||
| ≤1 time/month | 24·7 | 21·1, 28·3 | 6·8 | 0·020 |
| 2–3 times/month | 21·1 | 17·1, 25·0 | 9·4 | |
| 1–4 times/week | 30·8 | 27·6, 34·1 | 16·1 | |
| ≥5 times/week | 23·4 | 20·2, 26·5 | 13·1 | |
| FD† (n 1908) | ||||
| ≤1 time/month | 25·5 | 22·1, 29·1 | 6·6 | 0·053 |
| 2–3 times/month | 17·2 | 14·8, 19·8 | 15·1 | |
| 1–4 times/week | 30·8 | 27·7, 34·1 | 14·5 | |
| ≥5 times/week | 26·5 | 22·8, 30·6 | 11·8 | |
| ndSD‡ (n 1858) | ||||
| ≤1 time/month | 20·8 | 17·1, 25·1 | 11·6 | 0·932 |
| 2–3 times/month | 19·9 | 16·8, 23·5 | 11·6 | |
| 1–4 times/week | 41·8 | 37·5, 46·3 | 11·6 | |
| ≥5 times/week | 17·4 | 13·9, 21·5 | 13·5 | |
| tEFF§ (n 1961) | ||||
| ≤1 time/month | 3·6 | 2·2, 5·9 | 3·7 | 0·020 |
| 2–3 times/month | 4·3 | 3·0, 6·2 | 2·5 | |
| 1–4 times/week | 36·6 | 32·1, 41·2 | 11·0 | |
| ≥5 times/week | 55·5 | 50·6, 60·3 | 13·4 | |
| OJ|| (n 1961) | ||||
| ≤1 time/month | 22·0 | 18·5, 25·4 | 12·9 | 0·924 |
| 2–3 times/month | 21·1 | 17·8, 24·4 | 11·2 | |
| 1–4 times/week | 35·9 | 31·5, 40·2 | 11·8 | |
| ≥5 times/week | 21·1 | 17·3, 24·8 | 10·7 |
Significant associations are shown in bold font.
AJ (apple juice) is one of very few foods known to contain fructose in high relative proportion to glucose (approximately 2:1)( 23 ).
FD (non-diet fruit drinks) corresponds to sweetened fruit beverages, other than juices, known to contain high-fructose corn syrup (HFCS) as the main sweetener.
ndSD (non-diet soft drinks) corresponds to caffeinated and caffeine-free, non-diet soda; in 2003–2006 (the NHANES study period) HFCS was the main sweetener in soda( 47 ).
tEFF (total excess free fructose) combines average intake frequency for AJ+FD+ndSD.
OJ (orange juice) is not an EFF beverage and is included for comparison. The ratio of fructose to glucose is approximately 1:1( 23 ).