Table 3.
Summary risk estimates of the association between serum lipids and colorectal cancer and adenoma risk
| Heterogeneity test | ||||||
|---|---|---|---|---|---|---|
| Number of studies | P | RR | 95 % CI | P | Q | I 2 (%) |
| TC and colorectal cancer risk | ||||||
| Eight | 0·38 | 0·95 | 0·85, 1·06 | <0·00001 | 40·30 | 80 |
| TAG and colorectal cancer risk | ||||||
| Fourteen | 0·10 | 1·07 | 0·99, 1·15 | 0·01 | 31·81 | 50 |
| HDL-C and colorectal cancer risk | ||||||
| Nine | 0·77 | 0·97 | 0·80, 1·18 | 0·0001 | 33·01 | 73 |
| LDL-C and colorectal cancer risk | ||||||
| Three | 0·07 | 0·88 | 0·77, 1·01 | 0·07 | 5·34 | 63 |
| TC and colorectal adenoma risk | ||||||
| Nine | 0·02 | 1·04 | 1·01, 1·09 | 0·73 | 5·26 | 0 |
| TAG and colorectal adenoma risk | ||||||
| Sixteen | 0·0009 | 1·06 | 1·03, 1·10 | <0·00001 | 62·15 | 69 |
| HDL-C and colorectal adenoma risk | ||||||
| Fourteen | 0·12 | 1·03 | 0·99, 1·06 | 0·03 | 29·88 | 43 |
| LDL-C and colorectal adenoma risk | ||||||
| Five | 0·003 | 1·11 | 1·04, 1·19 | <0·00001 | 70·43 | 93 |
RR, risk ratio; TC, total cholesterol; HDL-C, HDL-cholesterol; LDL-C, LDL-cholesterol.