Fig. 5.

Protein-level evaluation of hyperoxia exposure responses mitigated in Cyp1b1-null mice. A. Selected pathways enriched by hyperoxia in WT (grey bars) and mitigated in Cyp1b1-null mice (green bars). B. Reverse Phase Protein Array (RPPA) to assess levels of proteins affected by hyperoxia and found in the enriched pathway genesets. Protein intensity values for each treatment are shown, with asterisks indicating significance (*p < 0.05, **p < 0.005, ***p < 0.0005). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)