Table 3:

Simple logistic regression models of ADRD risk in individuals of European ancestry as a function of age, Alzheimer’s disease polygenic risk scores (PRS), PTSD or TBI and their interactions with the PRS.

		OR (95% CI)	p-value
PTSD Model
	Age	1.11 (1.11, 1.11)	~0
	PTSD	2.61 (2.43, 2.79)	2.30e-162
	PRS	1.15 (1.13, 1.18)	1.11e-32
	PRS × PTSD	0.95 (0.89, 1.02)	0.14
TBI Model
	Age	1.10 (1.09, 1.10)	~0
	TBI	1.94 (1.82, 2.07)	2.49e-96
	PRS	1.15 (1.13, 1.17)	2.15e-44
	PRS × TBI	0.98 (0.92, 1.04)	0.57

Note: The parameter estimates for the main effects listed were derived from main effects-only models. The GxE parameter estimates were from models with the main effects and interaction term included in the same model.