Table 2 -.

Number and Percent of Healthy Subjects (HS) and Persons with Diabetes (DM) with Abnormality of Composite Measures of Attributes of Nerve Conduction Meeting DCCT Criteria

	3 HS Cohorts Combined		3 DM Cohorts Combined†		Difference in %	Fisher’s Exact Test
	Total n	n (%) Abnormal	Total n	n (%) Abnormal		p
1. ≥ 2 pts* of any of > 1 Nerve of Fibular, Ulnar or Tibial CMAPs, MNCVs or MNDLs or Sural SNAP or SNDL†	393	44 (11.20)	379	189 (49.87)	38.87	<0.0001
2. ≥ 2 pts of any of > 1 of Fibular, Tibial or Ulnar MNCV or Sural SNDL	394	15 (3.81)	376	151 (40.16)	36.35	<0.0001
3. ≥ 2 pts of any of > 1 of Ulnar or Fibular MNCV	395	8 (2.03)	383	83 (21.67)	19.64	<0.0001
4. ≥ 2 pts of any of > 1 of Fibular, Ulnar or Tibial CMAPs or Sural SNAP	395	9 (2.28)	388	72 (18.56)	16.28	<0.0001
5. ≥ 2 pts of any of > 1 of Ulnar or Tibial F-wave	394	10 (2.54)	380	48 (12.63)	10.09	<0.0001
6. ≥ 2 pts of any of > 1 of Ulnar MNCV or Sural SNAP	395	4 (1.01)	388	28 (7.22)	6.21	<0.0001

MNCV = motor nerve conduction velocity, F-wave = F-wave latency, SNDL = sensory nerve distal latency, SNAP = sensory nerve action potential amplitude, CMAP = compound muscle action potential amplitude, MNDL = motor nerve distal latency

^*> 5^th \ < 95^th = 0 pts (points); > 1^st to ≤ 5^th \ ≥ 95^th to < 99^th = 1 pt; ≤ 1^st \ ≥ 99^th = 2 pts

^†McNemar’s test (S; p) of differences of frequencies of abnormality between pairs of composite measures of attributes of nerve conduction: 1 vs. 2 (29.00; <0.0001), 1 vs. 4 (117.00; <0.0001), 2 vs. 4 (64.88; <0.0001)