Table 2.
Characteristics of study participants.
| Characteristics | POMS (n=490) | Healthy controls (n=716) | P-value |
|---|---|---|---|
| Age, median years (IQR) | 16 (3) | 15 (5) | 0.034a |
| Female, n (%) | 316 (64.3) | 420 (59.1) | 0.07b |
| Ratio, F:M | 1.8:1 | 1.44:1 | |
| Self-reported race, n (%) | |||
| White | 312 (68.9) | 439 (66.4) | 0.398b |
| Self-reported ethnicity, n (%) | |||
| Hispanic | 150 (32.1) | 156 (23) | <0.001b |
| Genetic ancestry estimation, mean (SD) | |||
| European ancestry percentage | 65.6 (0.3) | 66.7 (0.3) | 0.57c |
| East Asian ancestry percentage | 3.6 (0.2) | 8 (0.2) | 0.007c |
| Native American ancestry percentage | 10.2 (0.2) | 7.6 (0.2) | 0.006c |
| West African ancestry percentage | 19.5 (0.3) | 17.6 (0.3) | 0.23c |
| Mother’s education, n (%) | |||
| Less than high school | 52 (12.1) | 40 (6.4) | <0.001d |
| High school and college | 240 (56) | 295 (46.9) | |
| University degree | 137 (31.9) | 293 (46.7) |
POMS: Pediatric-onset multiple sclerosis; IQR: interquartile range; SD: standard deviation.
a
Mann Whitney test
b
Fisher’s exact test
c
Unpaired t-test
d
Chi-squared test