Table 1.

Optimization of gold-catalyzed oxo-arylfluorination^a

Entry	Variation of standard conditions	Yield(%)b
1	None	70
2	Ph3PAuCl (10 mol%)	58
3	dppm(AuCl)2 (5 mol%)	38
4	(4-CF3Ph)3PAuTFA (10 mol%)	53
5	(4-CF3Ph)3PAuOTs (10 mol%)	50
6	without (4-CF3Ph)3PAuCl	N.D.
7	H2O (5.0 equiv)	61
8	without H2O	49
9	NFSI instead of Selectfluor	N.D.

^aStandard reaction conditions: 1a (0.1 mmol), 2a (0.3 mmol), (4-CF₃Ph)₃PAuCl (10 mol%), Selectflour (4.0 equiv.), H₂O (2.0 equiv.), MeCN (2.0 mL), 50 °C, air, 12 h.

^bIsolated yields. dppm bis(diphenylphosphino)methane, Selectfluor 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate), NFSI N-fluorobenzenesulfonimide.