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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: J Biomol Struct Dyn. 2022 Dec 16;41(19):9808–9827. doi: 10.1080/07391102.2022.2153269

Figure 6: IPA Network Map of RNASeq and Protein Array Data.

Figure 6:

A) IPA generated network map showing known connections between the most common genes found in the RNASeq datasets and those found in the protein array with each other and EGFR. B) IPA generated network map showing known connections between the most common genes found in the RNASeq datasets and those found in the protein array with EGFR and known pathways in IPA for cellular signaling/ metabolic processes of interest. C) Gene expression in lapatinib and ketoconazole treated EGFR TKI tolerant cells compared to parental. H1975 cells were treated at seeding with 7.5μM lapatinib and/or 15μM ketoconazole for 72 hours. Average fold change ±SEM, compared to untreated, is shown (N=2). A 2-Way ANOVA and Uncorrected Fisher’s LSD post hoc tests were used to determine significance. * = p<0.05, ** = p<0.01.