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. 2000 Jun 15;28(12):2342–2352. doi: 10.1093/nar/28.12.2342

Figure 3.

Figure 3

A portion of the Cbf5p sequence alignment showing the region encompassing TruB motifs I and II. Motifs are adapted from Koonin (36), with highly conserved residues boxed. The position of the conserved, functionally important Asp (see text) is marked with an asterisk. Sequences shown above the Euglena sequence are eukaryotic, sequences below are archaebacterial. GenBank accession numbers are: S.cerevisiae, AAA34473; K.lactis, AAC64862; Candida albicans, AAB94297; Emericella nidulans, AAB94296; Sartorya (Aspergillus) fumigata, AAB94298; Schizosaccharomyces pombe, CAB10131; D.melanogaster, AAC97117; C.elegans, CAB07244; Homo sapiens, AAB94299; Rattus norvegicus, P40615; A.fulgidus, AAB90995; M.jannaschii, AAB98132; Pyrococcus abyssi, CAB49444; Pyrococcus horikoshii, O59357; M.thermoautotrophicum, O26140. The A.pernix sequence is a fusion of two peptide sequences (BAA79973 and BAA79974) encoded by separate open reading frames (nucleotide sequence AP000060.1). In the complete alignment (available from the authors on request), non-Cbf5p-homologous regions of these two peptides were excluded.