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. 2023 Jun 2;17:1174165. doi: 10.3389/fnins.2023.1174165

TABLE 6.

Speeded naming model interaction outputs.

Speeded naming combined scaled score Parameter estimate (SE) t p
Left AF FA
FA*age*group −48.79 (16.16) −3.019 0.0029**(0.0174)
FA*group 229.4 (86.73) 2.645 0.0088**
FA*age 43.62 (11.75) 3.714 0.00026***
Age*group 22.43 (7.28) 3.08 0.0023**
Left AF MD
MD*age*group 29.40 (13.54) 2.172 0.031*(0.093)
MD*group −141.75 (74.23) −1.91 0.0576
MD*age −24.24 (9.74) −2.49 0.0139*
Age*group −23.67 (11.23) −2.11 0.0362*
Right AF FA
FA*age*group −10.49 (11.08) −0.948 0.345
FA*group 63.82 (60.59) 1.053 0.294
FA*age 15.61 (8.17) 1.91 0.058
Age*group 5.12 (4.74) 1.081 0.281
Right AF MD
MD*age*group 16.1 (13.38) 1.203 0.231
MD*group −83.8 (73.9) −1.133 0.259
MD*age −3.7 (7.93) −0.467 0.641
Age*group −12.86 (11.11) −1.158 0.248
Laterality index FA
LI*age*group −10.05 (9.75) −1.031 0.3038
LI*group 37.17 (54.35) 0.685 0.494
LI*age 3.12 (7.79) 0.4 0.689
Age*group 0.77 (0.48) 1.595 0.112
Laterality index MD
LI*age*group 15.03 (27.07) 0.555 0.579
LI*group −65.72 (144.85) −0.454 0.651
LI*age −24.61 (16.14) −1.525 0.130
Age*group 0.49 (0.39) 1.235 0.218

Results are shown for the linear mixed effects models that compared diffusion-age-group interactions in predicting SN scores. Only the interaction terms and the intercept are shown. Stars correspond to the following p-values: *(p < 0.05), **(p < 0.01), ***(p < 0.001). Significant three-way interactions that survived multiple comparison correction (q < 0.05) are bolded, with the corresponding q value in parentheses. Nominally significant three-way interactions that failed to survive multiple comparison correction are italicized, with the corresponding q value in parentheses. Significant two-way interactions and intercepts are starred, but not bolded, as these were not corrected for. AF, arcuate fasciculus; SE, standard error; FA, fractional anisotropy; MD, mean diffusivity; LI, laterality index.