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. 2023 Jun 2;14:1174968. doi: 10.3389/fmicb.2023.1174968

Figure 1.

Figure 1

Changes in indicators related to constipation by multi-strain probiotics Consti-Biome. (A) Showed experimental scheme. (B); number of fecal pellets, (C); Fecal pH, (D); Fecal water content, (E); gastrointestinal transit rate of normal control (NOR), loperamide administration (LOP), positive control (PC), low concentration multi-strain probiotics administration (G1, 2 × 108 cfu/mL), medium concentration multi-strain probiotics administration (G2, 2 × 109 cfu/mL), and high concentration probiotic administration (G3, 2 × 1010 cfu/mL) groups. Data were collected 2 weeks after treatment. Data are mean ± SEM of 7 animals. *p < 0.05, **p < 0.01, *** p < 0.001, **** p < 0.0001, significantly different from the LOP as per one-way ANOVA with the Tukey’s multiple comparisons test.