Table 4.
Associations of gut leakage markers, microbial metabolites and cardiac function with the microbiota Shannon diversity index (n = 124).
| Shannon index | ||
|---|---|---|
| Spearman's rho | p-value | |
| LPS | 0.16 | 0.08 |
| LBP | −0.12 | 0.16 |
| I-FABP | −0.30 | 0.00* |
| sCD14 | 0.01 | 0.87 |
| Butyratea | 0.19 | 0.05* |
| TMAO | −0.08 | 0.38 |
| NT-proBNP | 0.15 | 0.09 |
| LVEF | 0.15 | 0.08 |
Statistically significant p-values are marked with an asterisk.
Predicted butyrate producing capacity.
NT-proBNP, N-terminal pro-B-type natriuretic peptide; LVEF, left ventricular ejection fraction; LPS, lipopolysaccharide; LBP, LPS-binding protein; I-FABP, intestinal fatty acid binding protein; sCD14, soluble cluster of differentiation 14; TMAO, trimethylamine N-oxide; NT-proBNP, N-terminal pro-B-type natriuretic peptide; LVEF, left ventricular ejection fraction.