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. 2023 Jun 2;17:1130169. doi: 10.3389/fnana.2023.1130169

Figure 12.

Figure 12

Vessels and S100B-ir cells in the mouse colon. The vessels were painted by WGA (cyan) and cells were immunostained by S100B (red). All the images are samples from the proximal colon. (A, B) S100B-ir cells in the submucosal plexus and myenteric plexus, respectively. The capillaries did not get into either of the plexuses. (C): S100B-ir cell bodies and processes surrounded vessels in the submucosa. (D) S100B-ir cells and microvessels in the circular muscle layer. (E) In the submucosal layer, S100B-ir cells formed in a net close to the capillary net at the bottom of mucosal crypts. (F) S100B-ir cells located close to the top mucosal capillary network. Arrow indicates S100B labels under the capillary rings. (G) Transverse section of a mucosal fold in the proximal colon showing S100B-ir cells located densely in the lower portion of mucosa and lamina propria (arrows). (H, I) High magnifications demonstrate some S100B-ir processes at the top of mucosal crypts while not in apposition to the capillaries. The image in (I) is tilted to show the locations of capillaries and S100B-ir processes (arrows).