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. 2023 Jun 2;10:1170696. doi: 10.3389/fmed.2023.1170696

Table 2.

Results of sex differences and correlation analysis stratified by sex.

Sex differences Correlation analysis with axial length
Women (n = 275) Men (n = 185) Women Men
Mean Mean P -value ß ( p -value) Adjusted ß ( p -value) a ß ( p -value) Adjusted ß ( p -value) a
Age (y) 74.3 ± 8.8 72.7 ± 9.3 0.071 −0.401 (< 0.001*) −0.346 (< 0.001*)
Axial length (mm) 23.92 ± 1.66 24.44 ± 1.48 < 0.001*
Spherical equivalent (diopter) −1.83 ± 4.27 −2.58 ± 3.99 0.263 −0.720 (< 0.001*) −0.673 (< 0.001*) −0.824 (< 0.001*) −0.671 (< 0.001*)
Tear break-up time (s) 3.0 ± 2.2 4.2 ± 2.0 < 0.001* −0.006 (0.911) 0.048 (0.405) 0.020 (0.796) 0.027 (0.707)
Strip meniscometry value (mm) 1.7 ± 2.5 2.6 ± 3.0 0.007* −0.163 (0.039*) −0.142 (0.057) 0.043 (0.672) −0.004 (0.966)
Corneal staining score 0.3 ± 0.5 0.1 ± 0.3 < 0.001* −0.019 (0.758) −0.032 (0.573) 0.056 (0.469) 0.002 (0.972)
Endothelial cell density (cells/mm2) 2,667 ± 352 2,737 ± 306 0.030* −0.139 (0.021*) −0.148 (0.007*) 0.081 (0.281) 0.056 (0.412)
Dry eye medication (%) 18.7 5.9 < 0.001* 0.034 (0.573) 0.054 (0.333) 0.072 (0.324) 0.042 (0.543)
Full macular thickness (μm) 254.4 ± 28.4 269.2 ± 32.7 0.001* 0.142 (0.092) 0.170 (0.034*) 0.143 (0.209) 0.183 (0.077)
Ganglion cell complex thickness (μm) 78.0 ± 15.7 82.0 ± 14.9 0.033* −0.250 (< 0.001*) −0.248 (< 0.001*) −0.051 (0.597) −0.002 (0.978)
Peripapillary NFL thickness (μm) 109.7 ± 22.3 106.5 ± 19.1 0.178 −0.367 (< 0.001*) −0.382 (< 0.001*) −0.228 (0.007*) −0.234 (0.003*)
*

P < 0.05, standardized partial regression coefficient and comparison using t-test.

a

Adjusted for age and sex.

NFL, nerve fiber layer.