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. 2023 Jun 2;14:1196446. doi: 10.3389/fneur.2023.1196446

Table 1.

Characteristics of systematic review and meta-analyses included in the review.

Variable Category Frequency (%)
Publication year 2008–2013 5 (21.7)
2014–2018 7 (30.4)
2019–2023 11 (47.8)
Number of authors Mean ± SD (range) 5.6 ± 2.7 (1–9)
Two authors 4 (17.4)
Multiple authors (>2 authors) 19 (82.6)
Number of studies included Total (median) 413 (13)
Mean ± SD (range) 18.0 ± 13.5 (1–62)
Summary findings Systematic review only 7 (30.4)
Meta-analysis only 8 (34.8)
Combination of both (systematic review and meta-analysis) 6 (26.1)
Meta-analysis and qualitative review 1 (4.3)
Network meta-analysis 1 (4.3)
Number of databases included in search Mean ± SD (range) 8.0 ± 3.1 (1–12)
3–4 2 (8.7)
5–7 11 (47.8)
8–10 6 (26.1)
>10 4 (17.4)
Other search strategies used (not mutually exclusive) Not reported (No other strategies were used) 8 (34.8)
Search reference list of included studies 8 (34.8)
Other additional searches done (online/through reviews/personal database) 3 (13.0)
Combination of both 4 (17.4)
Search start date Setting up a database 13 (56.5)
1950–1979 2 (8.7)
1980–2009 2 (8.7)
2010–2023 2 (8.7)
Not reported 4 (17.4)
Search end date Before 2010 3 (13.0)
2010–2014 3 (13.0)
2015–2019 10 (43.5)
2020–2022 7 (30.4)
Participant inclusion criteria: Age No limit 12 (52.3)
Not reported/stated 11 (47.8)
Participant inclusion criteria: Sex No limit 11 (47.8)
Not reported/stated 12 (52.3)
Study design inclusion criteria (not mutually exclusive) Randomized controlled trials 20 (87.0)
Randomized controlled design 2 (8.7)
Randomized controlled trials and Semi-randomized controlled clinical trial and Controlled clinical trials with the word randomized but without a specific description of the randomized method 1 (4.3)
Language inclusion criteria Two languages 7 (30.4)
Multiple languages 9 (39.1)
Not reported 7 (30.4)
Reporting guidelines Yes 6 (26.1)
No 17 (73.9)
Registered in PROSPERO Yes 3 (13.0)
No 20 (87.0)
Quality assessment of the studies included in the systematic reviews and meta-analyses Reported but no categorization possible 8 (34.8)
Reported with categorization 14 (60.9)
Not reported 1 (4.3)
Quality of the primary studies (n = 242) included in the systematic reviews and meta-analyses where quality was reported with categorization (n = 14) High 45 (18.6)
Moderate 44 (18.2)
Low 106 (43.8)
Undetermined (unclear) 47 (19.4)
Quality assessment tools used in the systematic reviews and meta-analyses Not reported (or not applicable) 2 (8.7)
Adapted/modified from previous study or tool 3 (13.0)
Cochrane Collaboration's Tool for Assessing Risk of Bias 15 (65.2)
Others 3 (13.0)