Fig. 9.

Pairwise comparisons between complete pOXA-48-like plasmids from ST307 demonstrate multiple independent deletions of regions adjacent to an IS1R element. One plasmid (from ARGID_31642), which possesses the classic pOXA-48-like backbone and which lacks these deletions, is included. ORFs are depicted as arrows with resistance genes (including bla _OXA-48/bla _OXA-244) labelled. Grey blocks between plasmid pairs indicate regions of homology. ORFs coloured blue are predicted to be involved in conjugation, while those in red have other predicted functions. The oriT region is indicated if identified in the plasmid.