TABLE 7.
Broad sense heritability (H2) and genetic coefficient of variance (CVg) at the initial and pretreatment as well post‐treatment of NDM of the absolute (A) and percentage (B) FBG in female and male mice of 13 different CC lines at the initial time point of the experiment (FBG0), week 12 (pretreatment (FBG12)) and at week 18 weeks (post‐treatment (FBG18)) maintained on CHD or HFD and after treatment with NDM between weeks 12 and 18
| A. Absolute FBG | ||||||||
|---|---|---|---|---|---|---|---|---|
| Time point | CHD (5% fat) | HFD (42% fat) | ||||||
| H2 | CVg | H2 | CVg | |||||
| ♀ | ♂ | ♀ | ♂ | ♀ | ♂ | ♀ | ♂ | |
| Initial | 0.56 | 0.59 | 0.16 | 0.18 | 0.56 | 0.59 | 0.16 | 0.18 |
| Pre‐treatment | 0.39 | 0.63 | 0.13 | 0.23 | 0.60 | 0.64 | 0.16 | 0.23 |
| Post‐treatment | 0.80 | 0.43 | 0.26 | 0.16 | 0.50 | 0.73 | 0.15 | 0.28 |
| B. % FBG | ||||||||
|---|---|---|---|---|---|---|---|---|
| Phenotype | CHD (5% fat) | HFD (42% fat) | ||||||
| H2 | CVg | H2 | CVg | |||||
| ♀ | ♂ | ♀ | ♂ | ♀ | ♂ | ♀ | ♂ | |
| % FBG 0–12 | 0.15 | 0.10 | −1.3 | −1.8 | 0.34 | 0.51 | 2.51 | 3.53 |
| % FBG 12–18 | 0.47 | 0.43 | −2.9 | −3.8 | 0.46 | 0.63 | 3.43 | −3.09 |