Regulatory network of circ_NRIP1 in human malignant tumors. (A) Ovarian cancer, (B) breast cancer, (C) esophageal squamous cell cancer, (D) papillary thyroid carcinoma, (E) colorectal cancer, (F) gastric cancer, (G) osteosarcoma, (H) nasopharyngeal carcinoma and (I) cervical cancer. HOXC8, homeobox C8; MMP2, matrix metalloproteinase 2; MMP9, matrix metalloproteinase 9; PTP4A1, protein tyrosine phosphatase 4A1; ERK1, extracellular regulated protein kinase1; ERK2, extracellular regulated protein kinase2; FOXC2, forkhead box C2; AKT3, AKT serine/threonine kinase 3; PI3K, phosphatidylinositol 3-kinase; DDAH1, dimethylarginine dimethylaminohydrolase 1; ZEB2, zinc finger E-box binding homeobox 2; EMT, epithelial-mesenchymal transition; MYH9, myosin heavy chain 9; AKT1, AKT serine/threonine kinase 1; SNAI1, snail family transcriptional repressor 1; SEMA4D, semaphoring 4D; IL-25, interleukin 25; PBX3, pre-B-cell leukemia homeobox 3; JAK2, Janus kinase 2; STAT1, signal transducer and activator of transcription 1; p38, p38 kinase.