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. 2023 Jun 16;78(Suppl 1):38–43. doi: 10.1093/gerona/glad022

Table 2.

Capromorelin Study of Older Subjects at Risk of Functional Decline

Change Versus Baseline 
at 12 Months
Placebo (kg) Capromorelin (kg)
FFM 0.6 + 1.4 1.6 + 3.2 p = .02
Body weight −0.1 + 2.2 1.2 + 5.2 p = .06

Notes: IGF-I levels in capromerlin- versus placebo-treated subjects increased by ~1.5-fold p = .001. FFM = fat-free mass; IGF-1 = insulin-like growth factor