Table 3.
Summary of pooled positivity rates of high-risk individuals, compliance rates of endoscopy examinations, and prevalence of endoscopy findings in population-based esophageal cancer (EC) screening in China by region.
| Assessed metrics in population-based EC screening | High-risk areas | Rural China | Urban China | |||||
|
|
Pooled rate, % (95% CI) | I 2 | Pooled rate, % (95% CI) | I 2 | Pooled rate, % (95% CI) | I 2 | ||
| Positivity rates of high-risk individuals in EC screening |
—a | — | 44.12 (28.76-60.69) | 100% | 23.11 (19.52-27.13) | 100% | ||
| Compliance rates of endoscopy examinations | 50.11 (36.65-63.58) | 100% | 52.40 (44.58-60.22） | 100% | 23.67 (18.24-29.10) | 100% | ||
| Endoscopy findings | ||||||||
|
|
Negative endoscopy findings | 94.72 (92.82-96.14) | 100% | 96.93 (92.99-98.68) | 99% | 99.41 (99.07-99.62) | 82% | |
|
|
LGINb | 3.99 (2.78-5.69) | 100% | 2.55 (1.03-6.19) | 99% | 0.34 (0.14-0.81) | 84% | |
|
|
Positive cases | 1.03 (0.82-1.30) | 98% | 0.48 (0.25-0.93) | 98% | 0.12 (0.07-0.21) | 46% | |
|
|
Early detection rates | 82.09 (74.85-87.59) | 93% | 80.76 (69.24-88.68) | 93% | 80.08 (27.21-97.74) | 85% | |
aNot applicable.
bLGIN: low-grade intraepithelial neoplasia.