Table 3.

Poisson regression of peak DRS ∼ POD1 change in plasma amyloid. Based on Cook's distances for univariate peak DRS ∼ amyloid regression, six, seven, and three outliers were excluded for Aβ40, Aβ42, and AβR, respectively. Aβ, amyloid beta; AβR, amyloid beta ratio; AIC, Akaike's information criteria; BIC, Bayesian information criteria; CI, confidence interval; df, degrees of freedom; DRS, Delirium Rating Scale; IRR, incidence rate ratio; POD, postoperative day; se, standard error; TMTB, Trail Making Test B. Aβ40: AIC=594; BIC=606. Aβ42: AIC=596; BIC=607. AβR: AIC=665; BIC=677. ∗P<0.05; ∗∗P<0.01; ∗∗∗P<0.001.

Characteristic	Aβ40					Aβ42					AβR
	N	Log(IRR)	se	95% CI	P-value	N	Log(IRR)	se	95% CI	P-value	N	Log(IRR)	se	95% CI	P-value
Unadjusted analysis
(Intercept)	85	2.4	0.033	2.4–2.5	<0.001∗∗∗	84	2.4	0.033	2.3–2.5	<0.001∗∗∗	88	2.4	0.033	2.4–2.5	<0.001∗∗∗
POD1 change in plasma amyloid	85	–0.31	0.092	–0.48 to –0.13	<0.001∗∗∗	84	–0.19	0.18	–0.55 to 0.16	0.29	88	0.57	0.152	0.26–0.86	<0.001∗∗∗
Adjusted analysis
(Intercept)	77	2.97	0.559	1.88–4.07	<0.001∗∗∗	77	3.14	0.56	2.049–4.24	<0.001∗∗∗	79	3.36	0.540	2.30–4.42	<0.001∗∗∗
POD1 change in plasma amyloid	77	–0.22	0.100	–0.42 to –0.029	0.023∗	77	–0.13	0.20	–0.523 to 0.24	0.49	79	0.43	0.294	–0.13 to 1.02	0.14
Age	77	–0.010	0.008	–0.026 to 0.0057	0.21	77	–0.013	0.008	–0.029 to 0.0028	0.11	79	–0.016	0.008	–0.031 to –0.0007	0.042∗
Sex: male	77	–0.18	0.070	–0.32 to –0.042	0.010∗	77	–0.15	0.070	–0.287 to –0.012	0.034∗	79	–0.11	0.068	–0.25 to 0.020	0.094
TMTB baseline	77	0.0023	0.001	0.0009–0.004	<0.001∗∗∗	77	0.0025	0.001	0.001–0.004	<0.001∗∗∗	79	0.0026	0.001	0.0013–0.0039	<0.001∗∗∗