Table 5.
Observed and fitteda cancers of the esophagus by dose category for various risk factors
| Dose (Gy) | People | person yearsb | Cases | Fitted Values |
|||
|---|---|---|---|---|---|---|---|
| Total | Backgroundc | Non-radiation excessd | Radiation Excess | ||||
|
| |||||||
| < 0.005 | 60,983 | 1,787,606 | 276 | 268.5 | 81.8 | 186.7 | 0.0 |
| − 0.1 | 27,536 | 808,203 | 130 | 130.1 | 39.1 | 91.0 | 0.1 |
| − 0.2 | 5,584 | 163,606 | 21 | 25.9 | 8.2 | 17.6 | 0.2 |
| − 0.5 | 5,931 | 169,815 | 29 | 27.3 | 8.4 | 17.9 | 0.9 |
| − 1 | 3,216 | 90,718 | 13 | 16.7 | 4.4 | 9.9 | 2.4 |
| − 2 | 1,628 | 44,903 | 9 | 12.3 | 2.1 | 5.4 | 4.8 |
| 2+ | 566 | 14,642 | 8 | 5.2 | 0.6 | 1.7 | 2.9 |
|
| |||||||
| Total | 105,444 | 3,079,492 | 486 | 486.0 | 144.6 | 330.2 | 11.3 |
|
| |||||||
| Male | 42,910 | 1,142,236 | 394 | 394.0 | 65.7 | 318.8 | 9.6 |
| Female | 62,534 | 1,937,256 | 92 | 92.0 | 78.9 | 11.4 | 1.7 |
Fitted cases were based on quadratic multiplicative dose-response model for all esophageal cancers with no sex difference in the risk.
The person-years showed were rounded; the sum of the numeric totals does not necessarily equal the total in lowest row.
Background cases are the expected number of cases in that would be expected on the cohort if there was no smoking, alcohol consumption or radiation exposure.
The estimated number of esophageal cancers associated with alcohol and or smoking. The estimated number of smoking associated cases was 257.3 while 213.8 cases were estimated to be associated with alcohol drinking. N.B. since the estimates are based on a multiplicative model they include each 141.0 cases estimated to be associated with the joint effect of smoking and alcohol drinking.