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. Author manuscript; available in PMC: 2023 Jun 16.
Published in final edited form as: Radiat Res. 2019 Jul 29;192(3):331–344. doi: 10.1667/RR15386.1

Table 5.

Observed and fitteda cancers of the esophagus by dose category for various risk factors

Dose (Gy) People person yearsb Cases Fitted Values
Total Backgroundc Non-radiation excessd Radiation Excess

< 0.005 60,983 1,787,606 276 268.5 81.8 186.7 0.0
− 0.1 27,536 808,203 130 130.1 39.1 91.0 0.1
− 0.2 5,584 163,606 21 25.9 8.2 17.6 0.2
− 0.5 5,931 169,815 29 27.3 8.4 17.9 0.9
− 1 3,216 90,718 13 16.7 4.4 9.9 2.4
− 2 1,628 44,903 9 12.3 2.1 5.4 4.8
2+ 566 14,642 8 5.2 0.6 1.7 2.9

Total 105,444 3,079,492 486 486.0 144.6 330.2 11.3

Male 42,910 1,142,236 394 394.0 65.7 318.8 9.6
Female 62,534 1,937,256 92 92.0 78.9 11.4 1.7
a

Fitted cases were based on quadratic multiplicative dose-response model for all esophageal cancers with no sex difference in the risk.

b

The person-years showed were rounded; the sum of the numeric totals does not necessarily equal the total in lowest row.

c

Background cases are the expected number of cases in that would be expected on the cohort if there was no smoking, alcohol consumption or radiation exposure.

d

The estimated number of esophageal cancers associated with alcohol and or smoking. The estimated number of smoking associated cases was 257.3 while 213.8 cases were estimated to be associated with alcohol drinking. N.B. since the estimates are based on a multiplicative model they include each 141.0 cases estimated to be associated with the joint effect of smoking and alcohol drinking.