Table 4.

Changes in EORTC QLQ-C30 domains from diagnosis to the pandemic time point for the control group.

EORTC QLQ-C30 Domain		Diagnosis timepoint		Pandemic timepoint		P-value (Mann Whitney test)
		Mean (SD)	Median (IQR)	Mean (SD)	Median (IQR)
Functional scales	Physical function	73.14 (28.47)	87.00 (61.75–93.00)	82.22 (21.29)	87.00 (80.00–100.00)	0.043
	Role function	63.83 (33.98)	87.00 (41.50–100.00)	76.89 (30.84)	83.00 (67.00–100.00)	0.139
	Emotional function	78.03 (19.73)	100.00 (83.00–100.00)	80.22 (17.94)	83.00 (75.00–92.00)	0.726
	Cognitive function	92.53 (12.27)	100.00 (83.00–100.00)	90.28 (18.35)	100.00 (83.00–100.00)	0.885
	Social function	92.06 (18.06)	100.00 (83.00–100.00)	93.86 (12.15)	100.00 (87.25–100.00)	0.850
	Quality of Life	67.92 (22.26)	83.00 (50.00–83.00)	76.78 (18.76)	83.00 (67.00–83.00)	0.022
Symptomatic scales	Dyspnea	0.92 (5.50)	0.00 (0.00–0.00)	2.75 (9.25)	0.00 (0.00–0.00)	0.317
	Pain	18.03 (21.59)	8.50 (0.00–33.00)	17.58 (20.27)	17.00 (0.00–33.00)	0.952
	Fatigue	15.81 (19.08)	11.00 (0.00–33.00)	16.75 (20.39)	11.00 (0.00–33.00)	0.842
	Insomnia	0.00 (21.78)	0.00 (0.00–33.00)	12.86 (18.21)	0.00 (0.00–33.00)	0.106
	Loss of appetite	2.78 (12.31)	0.00 (0.00–0.00)	4.61 (14.13)	0.00 (0.00–0.00)	0.577
	Nausea	0.47 (2.83)	0.00 (0.00–0.00)	6.03 (19.17)	0.00 (0.00–0.00)	0.109
	Constipation	6.42 (13.25)	0.00 (0.00–0.00)	8.33 (20.17)	0.00 (0.00–0.00)	0.339
	Diarrhea	0.00 (0.00)	0.00 (0.00–0.00)	1.83 (7.67)	0.00 (0.00–0.00)	0.157
	Financial difficulties	3.69 (13.28)	0.00 (0.00–0.00)	4.61 (14.13)	0.00 (0.00–0.00)	0.783

SD, Standard Deviation; IQR, interquartile range. Mean and median scores of the EORTC QLQ-C30 domains at diagnosis and during the pandemic for patients in the Control group. The domains are divided into functional scales, for which a higher score corresponds to a better function, and symptomatic scales, for which the lower score corresponds to the absence of symptoms. Bold values indicated statistically significant results.