Table 5.

Changes in EORTC QLQ-C30 domains from diagnosis to the pandemic timepoint for the COVID group.

EORTC QLQ-C30 Domain		Diagnosis timepoint		Pandemic timepoint		P-value (Mann Whitney test)
		Mean (SD)	Median (IQR)	Mean (SD)	Median (IQR)
Functional scales	Physical function	69.33 (28.92)	80.00 (52.25–93.00)	66.55 (25.40)	70.00 (45.25–88.50)	0.543
	Role function	71.41 (33.59)	83.00 (50.00–100.00)	67.00 (39.13)	67.00 (17.00–100.00)	0.044
	Emotional function	71.83 (23.31)	83.00 (58.00–92.00)	71.95 (22.27)	75.00 (58.00–92.00)	0.900
	Cognitive function	93.62 (12.18)	100.00 (100.00–100.00)	93.19 (13.36)	100.00 (100.00–100.00)	0.740
	Social function	82.95 (29.79)	100.00 (100.00–100.00)	86.91 (23.97)	100.00 (100.00–100.00)	0.628
	Quality of Life	68.52 (25.21)	83.00 (50.00–83.00)	69.91 (17.73)	67.00 (67.00–83.00)	0.263
Symptomatic scales	Dyspnea	5.29 (15.98)	0.00 (0.00–0.00)	4.71 (11.69)	0.00 (0.00–0.00)	1.000
	Pain	20.64 (24.08)	17.00 (0.00–33.00)	22.62 (24.08)	17.00 (0.00–33.00)	0.361
	Fatigue	21.10 (26.88)	5.50 (0.00–33.00)	27.95 (23.52)	22.00 (11.00–44.00)	0.060
	Insomnia	21.36 (26.38)	0.00 (0.00–0.00)	26.93 (27.85)	33.00 (0.00–33.00)	0.093
	Loss of appetite	4.74 (13.88)	0.00 (0.00–0.00)	3.95 (13.16)	0.00 (0.00–0.00)	0.783
	Nausea	4.76 (12.88)	0.00 (0.00–0.00)	3.57 (11.94)	0.00 (0.00–0.00)	0.438
	Constipation	7.90 (20.55)	0.00 (0.00–0.00)	7.14 (21.53)	0.00 (0.00–0.00)	1.000
	Diarrhea	0.00 (0.00)	0.00 (0.00–0.00)	1.60 (10.34)	0.00 (0.00–0.00)	0.317
	Financial difficulties	11.10 (21.71)	0.00 (0.00–8.25)	15.83 (29.66)	0.00 (0.00–33.00)	0.223

SD, Standard Deviation; IQR, interquartile range. Mean and median scores of the EORTC QLQ-C30 domains at diagnosis and during the pandemic for patients in the COVID group. The domains are divided into functional scales, for which a higher score corresponds to a better function, and symptomatic scales, for which the lower score corresponds to the absence of symptoms. Bold values indicated statistically significant results.