Fig. 1.
Differentially expressed cytokines between control samples and CNV groups on days 3, 7, and 14 measured using a multiplex quantitative cytokines array (p < 0.001, fold change >2.0). MIP-1a was the most significantly upregulated cytokine on day 3 after laser induction (p < 0.001, fold change >10.0). MCP-5 and Fas-L were the 2 most significantly upregulated cytokines on day 7 after laser induction (p < 0.001, fold change >10.0). IL-15 and IL-7 were the 2 most significantly upregulated cytokines on day 14 after laser induction (p < 0.001, fold change >10.0). Data are presented as mean + SEM, n = 3 for each time point. **p < 0.001 versus control. CNV, choroidal neovascularization; MIP, macrophage inflammatory protein; MCP, monocyte-chemoattractant protein; Fas-L, Fas ligand; IL, interleukin.