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. 2023 Jan 25;17(6):933–942. doi: 10.1093/ecco-jcc/jjad013

Table 2.

Thioguanine dosages and adjustments during therapy

CD [N = 66] UC [N = 42] Total [N = 108]
TG dosage at baseline
 10 mg/day 6 [9%] 10 [24%] 16 [15%]
 15 mg/day 1 [2%] 0 [0%] 1 [1%]
 20 mg/day 52 [79%] 30 [71%] 82 [76%]
 25 mg/day 7 [11%] 2 [5%] 9 [8%]
TG dosage at remission
 10 mg/day 4 [6%] 8 [19%] 12 [11%]
 15 mg/day 1 [2%] 0 [0%] 1 [1%]
 20 mg/day 53 [80%] 33 [79%] 86 [80%]
 25 mg/day 8 [12%] 1 [2%] 9 [8%]
Adjustments in dosages
 None 53 [80%] 23 [55%] 76 [70%]
 Increase 4 [6%] 3 [7%] 7 [7%]
 Decrease 2 [3%] 5 [12%] 7 [7%]
 Both increase and decrease 7 [11%] 11 [26%] 18 [17%]

Thioguanine [TG] treatment characteristics at baseline and during follow-up. CD: Crohn’s disease; UC: ulcerative colitis.