[Preprint]. 2023 Jul 5:2023.06.02.543459. Originally published 2023 Jun 6. [Version 2] doi: 10.1101/2023.06.02.543459

Table 4.

Biological processes affected based on non-MyoF proteins different between Y versus MA participants

PANTHER GO-Slim Biological process (GO ID)	Proteins altered (pathway proteins)	p-value
From 96 non-MyoF proteins higher in Y versus MA, pre- (p<0.01)
Organophosphate metabolism (GO:0019637)	14 (395)	<0.0001
From 447 non-MyoF proteins higher in MA, pre- versus Y (p<0.01)
mRNA export from nucleus (GO:0006406)	8 (33)	0.0042
lipid oxidation (GO:0034440)	7 (30)	0.0226
regulation of RNA splicing (GO:0043484)	10 (75)	0.0270
protein import (GO:0017038)	11 (89)	0.0195
translational elongation (GO:0006414)	27 (254)	<0.0001
tRNA metabolic process (GO:0006399)	12 (113)	0.0317
mitochondrion organization (GO:0007005)	15 (153)	0.0071
ubiquitin-dependent protein catabolic process (GO:0006511)	21 (294)	0.0102
cellular response to stress (GO:0033554)	27 (480)	0.0318

Biological pathways presented to be up- and down-regulated between age groups based on differential non-MyoF protein expression differences between age cohorts (i.e., Table 3 data).